RFA 6 - Submission Portal
Sixth Call for Proposals: Evaluate Canadian Biotechnologies with Randomized Controlled Trials
Welcome to the ACT Canada submission portal for the sixth request for applications (RFA 6). Your application must be submitted via this portal, emailed applications will not be accepted .
Please complete all questions in this portal and upload a single PDF of your application. Naming convention for the PDF should include a NPI last name and project title (e.g., "Smith_ProjectTitle.pdf").
Application Components:
Please refer to the Call for Proposals (link updated) for detailed breakdown of section requirements and scoring.
Summary : 1 page Written Proposal : 4 pages if written in English or 5 pages if written in French. Budget and justification : 1 page References, figures, or tables: 1 page (optional) Deadline: Submit by Sunday, January 5, 2025 at 11:59pm ET Late submissions will not be accepted. Once submitted, confirmation of receipt will be provided. If you do not hear back within 24 hours, please follow up to ensure successful delivery. If you have any concerns or questions about this application process, please contact the Coordinating Team at ACT.Canada@phri.ca by Friday, December 20th.
Thank you for your interest in the ACT Canada Consortium and for your application.
Please save progress as you go using the [Save & Return Later ] button at the bottom of the form. 1. Which ACT Canada Research Network has endorsed this application? Each ACT Network (link) can endorse a maximum of 3 applications Networks should endorse proposals most relevant to their constituents, especially their patients. No letter of support is required from the supporting ACT Network. 2. What is the trial name ? 3. What is the trial structure ? a) Phase b) Design (e.g. RCT)
Please save progress as you go using the [Save & Return Later ] button at the bottom of the form. 4. How many Principal Investigators are included in this application? PI(s) will have their substantive role in Canada for the duration of the project's term. their primary affiliation is in Canada; or they spend at least 50% of their time at the designated Canadian institution. PI(s) must report their shareholding status in the company. PI(s) can only submit one application to this competition. Full membership details can be included in the PDF. Select number of PIs max 3
4.1 Nominated Principal Investigator (PI1) Name, Email, Biotech Shareholding Status, Institution, and Province are required
4.2 Co - Principal Investigator (PI2) Name, Email, Biotech Shareholding Status, Institution, and Province are required
4.3 Co - Principal Investigator (PI3) Name, Email, Biotech Shareholding Status, Institution, and Province are required
5. Who is the Canadian Biotechnology Partner for this submission? Canadian-Controlled Private Corporation (CCPC) CCPC is a private corporation incorporated in Canada that is not controlled by non-residents or public corporations, meaning non-Canadian residents cannot directly or indirectly control the company or own more than 50% of the company or of its voting power via the board. Biotechnology , o r biotech, is the intersection of biological, engineering and computer sciences. Examples of biotech include the following: drug (including natural health products), living organisms (or parts of them), biological systems a) Company Name b) Business Number c) Product Type (e.g. drug, device, data system) d) Canadian controlled? e) Contact Name f) Contact Email g) Company Website (optional)
Please save progress as you go using the [Save & Return Later ] button at the bottom of the form. 6. Which Data Coordinating Centre is supporting this trial? a) Centre Name b) Centre Location
7. Please provide timeline and budget details a) End Date ACT funding must be used by June 30, 2026 b) Budget Request max $400,000 CAD c) Institution Holding Funds d) PDF includes the following statement: "I have confirmed my institution (which will hold the grant funds) has reviewed my proposed budget and deems all items to be CIHR eligible."
Please save progress as you go using the [Save & Return Later ] button at the bottom of the form. 8. Which email address should be used for correspondence and confirmation of submission? 9. PDF Checklist: We provide this checklist for your convenience only. It is your responsibility to ensure the PDF contains all requirements as described in the Call for Proposals (link updated) and to check each section for completion, accuracy, and eligibility. Eligibility Criteria Included in PDF? a) Leadership: The nominated principal investigator must be a Canadian researcher who is a member of an ACT Network. Leadership must be in partnership with a biotech company representative. b) PI applications: The nominated principal investigator(s) can only submit one application to this competition c) Canadian Biotech: The trial must evaluate a biotechnology and the biotechnology company partner must be Canadian-controlled.
d) Trial Design: The proposal is an RCT and not a product validation or observational study.
e) ACT Network: The trial must be endorsed by one of the 34 ACT Networks.
f) Budget: Investigators must provide confirmation from their institution that the proposed budget is CIHR eligible. ACT funding must be used by June 30, 2026.
g) Acknowledgement: Applicants will acknowledge ACT Consortium partnership and funding in all related presentations and publications.
h) Progress Report: If funded, applicants must be accountable for their progress, which will be summarized in annual ACT reports. A summary of their project will also be shared within ACT to raise awareness and foster new collaborations.
i) Open-Access: Applicants commit to making their trial results publicly available (open-access publication).
PDF is missing key information. Please revise PDF or application may be considered ineligible.
If there is a reason this has been excluded, please provide details here.
10. Submission PDF : Please submit a single PDF with file name that includes the NPI last name and project acronym (e.g., "Smith_ProjectAcronym.pdf"). Letters of support should not be included in the application. It is your responsibility to ensure the PDF contains all required components PDF File Select single file to upload
"Smith_ProjectAcronym.pdf"
Please submit application using the [SUBMIT] button at the bottom of the form.
1. ACT Network
* must provide value
CaDeN: Canadian Deprescribing Network CAIC: Canadian Association of Interventional Cardiology Clinical Trials Network CANet: Cardiovascular Network of Canada CanHMVr: The Canadian Home Mechanical Ventilation Research Network CANStim: Research in Non-Invasive Brain Stimulation CanStroke Recovery Trials Platform CANUCS: Canadian Collaborative on Urgent Care Surgery CCADN: Canadian Chronic Airway Disease Network CCARE-LTC: Collaborative for Caring for Long-Term Care CCCTG: Canadian Critical Care Trials Group CDTRP: Canadian Donation and Transplantation Research Program CEDRRN: Canadian COVID-19 Emergency Department Rapid Response Network CHF Alliance: Canadian Heart Function Alliance CIRN: Canadian Immunization Research Network CMCN: Canadian Medical Cannabis Clinical Trials Network CMDO: Cardiometabolic Health, Diabetes, and Obesity Research Network CNTN: Canadian Nephrology Trials Network CPN: Chronic Pain Network CRN-ACHDi: Canadian Research Network for Adult Congenital Heart Disease Interventions CSC: Canadian Stroke Consortium CSPIN: Canadian Stroke Prevention Intervention Network CTRC: Canadian Traumatic Brain Injury Research Consortium CYMH Trials Network: Canadian Network for Child and Youth Mental Health Trials DCTN: Diabetes Clinical Trials Network IMAGINE Network Infectious Disease Network INFORM RARE Network MICYRN: Maternal Infant Child and Youth Research Network OCOG: Ontario Clinical Oncology Group Orthopaedic Trauma Surgery Research Network PACT-V Heart Valve Network: Pan-Canadian Trial Network in Valvular Heart Disease PCPCRC: Pan-Canadian Palliative Care Research Collaborative Perioperative Care Network PIRN: Canadian Paediatric Inpatient Research Network test
2. b) Full name
* must provide value
3. a) Trial phase
* must provide value
3. b) Trial design
* must provide value
4. PI count choice
* must provide value
1 2 3
4.1 a) PI1 Name
* must provide value
4.1 a) PI1 Email
* must provide value
4.1 PI1 shareholding status
* must provide value
4.1 a) PI1 Province
* must provide value
4.1 a) PI1 Institution
* must provide value
4.1 a) PI1 Gender (optional)
4.1 a) PI1 Stage (optional)
4.2 b) PI2 Name
* must provide value
4.2 b) PI2 Email
* must provide value
4.2 PI2 shareholding status
* must provide value
4.2 b) PI2 Province
* must provide value
4.2 b) PI2 Institution
* must provide value
4.2 b) PI2 Gender (optional)
4.2 b) PI2 Stage (optional)
4.3 c) PI3 Name
* must provide value
4.3 c) PI3 Email
* must provide value
4.3 PI3 shareholding status
* must provide value
4.3 c) PI3 Province
* must provide value
4.3 c) PI3 Institution
* must provide value
4.3 c) PI3 Gender (optional)
4.3 c) PI3 Stage (optional)
5. a) biotech name
* must provide value
5. b) biotech business number
* must provide value
5. c) biotech product type
* must provide value
5. d) biotech Canadian Controlled
* must provide value
Yes No Unsure
details should be included in PDF
5. e) Biotech contact name
* must provide value
5. f) biotech contact email
* must provide value
5. g) biotech website (optional)
6. a) Data coord name
* must provide value
6. b) Data coord location
* must provide value
7. a) End date (max June 2026)
* must provide value
Today D-M-Y
7. b) budget total max 400,000
* must provide value
7. c) Institution Holding Funds
* must provide value
7. d) budget review statement (do not have required yes)
* must provide value
Yes No
8. correspondence email
* must provide value
Submit
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