The 2026 Breakthrough Awards: Personalized Medicine Focus are designed to accelerate promising, patient-impact-driven research that advances precision approaches to health and disease. We welcome applications spanning the full spectrum of personalized medicine, including biomarker discovery, genomics, diagnostics, targeted therapies, artificial intelligence and digital health, population health, health equity, implementation science, and other innovative areas that support more precise, predictive, and personalized care.

Please complete the following form to submit your application. Applications do not need to be completed in a single session; you will be able to save your progress and return to the application. Please complete all required sections before submitting your application. Incomplete applications will be removed from the competition.

Fall 2026 Breakthrough Awards Guidelines

Application requirements:

  • Application webform
  • 3-minute video pitch
  • (Optional) Voluntary Disclosure of Equity Data

Application Deadline: September 15, 2026 @ 4:00 PM ET

Awardees will be honoured at the HHS Research & Innovation Awards of Excellence on Wednesday, October 7, 2026 at Liuna Station. Please save the date in your calendar!

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